Aromasin (Exemestane) is an aromatase inhibitor of third generation. Aromatase is an enzyme that converts testosterone into estradiol (estrogen). The major application of Aromasin, as well as other aromatase inhibitors, is the treatment of estrogen dependent cancers in women. However, it gained popularity among bodybuilders, due to prevention of estrogen related side effects.
Many anabolics are prone to aromatization (conversion of androgens into estrogens), therefore they can increase the levels of estrogen and cause gynecomastia and water retention. While taking Exemestane during steroid cycle, one can reduce the level of estrogens by 85% and protect oneself against these side effects.
How Exemestane works
The action of Exemestane is similar to such aromatase inhibitors as Anastrozole and Letrozole. However, it has some advantages over them. Unlike non-steroidal inhibitors mentioned above, Aromasin can irreversibly block aromatase.
Besides this substance can stimulate the synthesis of endogenous testosterone, that is why some bodybuilders include this drug into PCT plan. Like Arimidex and Letrozole, Aromasin signals the pituitary gland to produce Luteinizing hormone (LH) and Follicle-stimulating hormone (FSH). These hormones induce the production of endogenous testosterone.
Moreover, Aromasin, unlike Femara and Arimidex, has the ability to increase the levels of IGF-1. This hormone has strong anabolic properties, which is beneficial during PCT.
How to use Aromasin
In case of treatment of estrogen dependent cancers, the usual dosage of Aromasin is 25 mg per day, until cancer remission comes. Usually, the treatment is followed by the usage of Nolvadex in order to prevent the return of cancer.
For bodybuilding purposes, the usual dosage of Exemestane is 12.5-25 mg every other day. Some bodybuilders take 25 mg/day before competitions. However, this dose is very high. In this case, you should control the levels of cholesterol and the period of Aromasin usage should not exceed 2 weeks.
Remember that estrogens are important for normal functioning of joints, immune system etc.
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