Modafinil is one of the most popular cognitive enhancement medications in the world. It’s similar in effect to amphetamines (Dexedrine and Adderall), or methylphenidate (Ritalin), but with much fewer side effects.
What Is Modalert?
Modalert is a generic version of modafinil made by the pharmaceutical giant, Sun Pharmaceuticals.
It comes in 100 mg, 200 mg, and 400 mg sizes, though most vendors sell the 200 mg version only. Each capsule comes with a convenient crease down the middle, so users can easily separate their 200 mg tablets into two equal 100 mg doses if they want a smaller dose.
Modalert is prescribed for treating ADD/ADHD and narcolepsy by doctors. Outside of its prescribed uses, Modalert is popular as a cognitive enhancement supplement. It’s also used by the US military to help their special forces stay awake during long missions.
Students often take Modalert to improve their focus during study sessions. Business executives use it to power through exhausting projects, and gamers use it during competitions to increase their vigilance and reaction times.
Modalert, like all modafinil, is considered a wakefulness-promoting and cognitive enhancing agent. It targets specific regions of the brain that are responsible for making us feel alert.
These effects are beneficial to a large range of people. Modafinil is popular among students, artists, writers, fighter pilots, shift workers, and virtually anybody who needs to stay awake to finish a tough project or tedious task.
The Benefits of Modalert
- Improved focus and concentration
- Increased energy levels
- Eliminates mental fatigue for several hours
- Improves the ability to perform tedious or repetitive tasks
- Increases motivation to work or study
How Modalert Works
Medications often work by binding to specific receptors in the body. The body uses different types of receptors to tell the cells what to do.
Modalert works on a special set of receptors called “dopamine transport receptors”
These receptors tell the neurons how much dopamine they should reabsorb (thus reducing the concentrations of dopamine). When Modalert enters the body, it blocks these receptors, preventing the reabsorption of dopamine. As less dopamine is reabsorbed into the cell, it begins to build up outside of the cell.
Cocaine uses the same mechanism to exert its effects, though to a much stronger degree. If we could imagine a dial in the brain controlling wakefulness, modafinil is about a 6, while cocaine is so powerful whole dial breaks off.
There are also several other mechanisms Modalert uses to boost cognitive function and wakefulness that make it very different than cocaine.
Modalert also increases histamine, orexin, and norepinephrine in the brain. These chemicals are used to regulate the arousal portion of the sleep-wake cycle. [1-3].
The conditions modafinil is prescribed for involve deficiencies in one or more of these neurotransmitters. ADD/ADHD sufferers often have below-average dopamine levels, and narcolepsy sufferers have low orexin.